Laboratory Cleanroom Solutions: Research, Testing, & Biosafety

I. Research Laboratories (Universities & Institutes)

1. Nanotechnology Labs

   • ISO Class 4 Modular Cleanrooms:
     FFUs with ULPA filters (99.9995% @ 0.12μm) for quantum dot synthesis and graphene research.

   • Vibration-Controlled Workstations:
     Active damping platforms (<0.2μm/s²) for atomic force microscopy (AFM) imaging.

2. Chemistry/Chemical Engineering Labs

   • Fume Hood Integration:
     Modular cleanrooms with acid-resistant walls + laminar flow hoods for solvent-free nanoparticle synthesis.

   • Gas Purge Pass Boxes:
     Transfer hygroscopic materials under nitrogen atmosphere.

II. Testing & Certification Centers

1. Microbial Testing Labs

   • ISO Class 5 Biosafety Cabinets:
     Integrated with FFUs for USP <61> compliance in bioburden testing.

   • Dual HEPA Air Showers:
     Eliminate 99.99% particulates before entering sterility testing zones (CFU ≤1/m³).

2. Environmental Monitoring

   • Mobile Cleanroom Modules:
     Deploy ISO Class 6 environments for on-site air/water quality analysis.

   • Particle Counting Calibration Zones:
     Laminar flow benches with ±3% measurement accuracy (0.3-5μm range).

III. CDC & Virology Facilities

1. BSL-3/BSL-4 Labs

   • Negative Pressure Cleanrooms:
     Leak-tight modular units with redundant HEPA filtration (EN 12469 compliance).

   • Double-Door Autoclave Pass Boxes:
     Decontaminate viral samples before transfer to BSL-2 areas.

2. Sample Processing

   • Class II Biosafety Cabinets:
     ULPA-filtered airflow for PCR prep and NGS library construction.

   • UV-Interlocked Transfer Hatches:
     Prevent accidental pathogen release during RNA extraction.

IV. Animal Research Laboratories

1. SPF Animal Housing

   • ISO Class 7 Barrier Systems:
     FFUs maintain ≤352,000 particles/m³ (≥0.5μm) with 12-15 air changes/hour.

   • Tunnel Washer Pass-Throughs:
     Sterilize cages without breaching containment.

2. Transgenic Animal Studies

   • IVF Workstations (ISO Class 5):
     Laminar flow + CO₂ incubators for embryo microinjection.

   • ESD-Safe Cleanrooms:
     Protect CRISPR gene editing equipment from static damage.

V. Core Advantages

• Flexible Configurations: Modular cleanrooms adapt to BSL-2 to BSL-4 requirements.

• Regulatory Compliance: Meet ISO 14644, WHO GLP, and NIH/CDC biosafety guidelines.

• Energy Efficiency: 30% energy savings via variable airflow FFUs vs. traditional HVAC.

• Real-Time Monitoring: IoT sensors track temperature, pressure, and particle counts 24/7.